Influence of the genetic polymorphism in the 5'-noncoding region of the CYP1A2 gene on CYP1A2 phenotype and urinary mutagenicity in smokers [An ... Toxicology and Environmental Mutagenesis] Free

Author: S. Pavanello
Edition:
Binding: Digital
ISBN: B000RR826A

Influence of the genetic polymorphism in the 5'-noncoding region of the CYP1A2 gene on CYP1A2 phenotype and urinary mutagenicity in smokers [An ... Toxicology and Environmental Mutagenesis]

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The functional significance of genetic polymorphisms on tobacco smoke-induced CYP1A2 activity was examined. The influence of three polymorphisms of the cytochrome P450 1A2 gene (CYP1A2) (-3860 G->A (allele *1C), -2467 T->delT (allele *1D), -163C->A (allele *1F)), located in the 5'-noncoding promoter region of the gene, on CYP1A2 activity (measured as caffeine metabolic ratio, CMR), was studied in Caucasian current smokers Check Influence of the genetic polymorphism in the 5'-noncoding region of the CYP1A2 gene on CYP1A2 phenotype and urinary mutagenicity in smokers [An ... Toxicology and Environmental Mutagenesis] our best diet books for 2013. All books are available in pdf format and downloadable from rapidshare, 4shared, and mediafire.